Electrocatalytic multicomponent assembling of phthalhydrazide, aldehydes and malononitrile: An efficient approach to 1H-pyrazolo[1,2-b]phthalazine-5,10-diones

Abstract

Electrocatalytic multicomponent transformation of phthalhydrazide, aromatic aldehydes and malononitrile in n -propanol in an undivided cell in the presence of sodium bromide as an electrolyte leads to 1 H -pyrazolo[1,2- b ]phthalazine-5,10-diones in short reaction times (4–8 min) and high yields (85–98%) at room temperature. The developed efficient electrocatalytic approach to the corresponding 1 H -pyrazolo[1,2- b ]phthalazine-5,10-diones is beneficial from the viewpoint of diversity-oriented large-scale processes and represents a new example of the ecologically pure synthetic concept for electrocatalytic multicomponent reactions strategy.