Electrocardiographic, clinical and haematological evaluation of propofol and xylazine-ketamine anaesthesia in Goat

Abstract

Limited information is available to ascertain the quality of intravenous anaesthetic regime predominantly practised in goats for short term surgical interventions. Clinical, electrocardiographic and haematological studies were conducted on twelve female Barbari crossbred goats, aged 2–4 years to assess the anaesthetic quality of propofol and xylazine-ketamine combination. Onset, duration and recovery from anaesthesia, clinical parameters (rectal temperature, pulse and respiratory rates), electrocardiography (ECG) and oxyhemoglobin (HbO2) saturation were assessed at 0, 10, 60, 120 min and haematological parameters at 0, 60, 180 min after propofol (4 mg/kg) and xylazine (0.05 mg/kg)-ketamine (4 mg/kg) were administered intravenously. Clinical and haematological parameters except lymphocyte count decreased. With stable plane of propofol anaesthesia, ECG amplitudes and heart rate increased while ECG intervals decreased. After ketamine induction, P wave amplitude, ECG intervals increased whereas R wave amplitude, heart rate decreased. Rectal temperature and pulse rate were better maintained in goats receiving propofol anaesthesia. Xylazine-ketamine exerted subtle deviation from pre-anaesthetic cardiovascular, respiratory, haematological parameters