Abstract
STUDIES have been made of lambs taken from their dams at 4 weeks of age and weaned, by stages, on to a selenium-deficient diet of the type used by Schwarz1 for the development of dietary hepatic necrosis in rats. Lambs on this diet develop muscular dystrophy, the lesions appearing in both the cardiac and skeletal musculature; the livers do not become necrotic as they do in the rat. Control lambs fed the same diet, supplemented with an oral drench of 10 mg of sodium selenite per week, do not develop muscular dystrophy.
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