Electrocardiogram of pigs in sagittal bipolar leads

Abstract

The similarity of porcine coronary circulation with humans [15], hemodynamic parameters [16] is suitable for using the porcine heart as an experimental model of cardiovascular diseases specific to humans. Pigs are a source of human valve bioprostheses [12]. Studies of pigs as donors for xenotransplantation have shown that it is impossible to unequivocally consider the heart of a pig to be identical to a human heart. The topography of the conducting system of the pig leads to significant differences in the sequence of depolarization of the heart ventricles, which must be taken into account when conducting electrocardiographic studies [3, 4].The aim of the study was to study the amplitude-temporal characteristics of the ECG in a normal pig. ECG in pigs was recorded in sagittal bipolar trunk leads according to Roshchevsky [7]. Animals were anesthetized with 1% solution of ventranquil (0,02 ml/kg), urethane (1,5 g/kg) intramuscularly. Heart rate in anesthetized pigs varied from 74 to 194 beats/min, the animals were divided into three groups. In the first group, animals with heart rate less than 100 beats/min, in the second from 100 to 150 beats/min, in the third more than 150 beats/min.In the course of the study, it was shown that in bipolar sagittal leads, the P-wave is positive single-phase; the most common configuration of the initial ventricular activity complex is rS; The T-wave is mostly positive. In animals from groups with significant differences in heart rate on the ECG in three bipolar sagittal leads, the shape and duration of the Q, R, S waves did not differ, the duration of the PQ and QT intervals differed significantly. The duration of the corrected QTc interval in animals with different heart rates practically did not differ.