Abstract
By calculating the Cohen coefficient, the force of the influence of an age factor on the dynamics of electrocardiographic parameters at development of a neuroleptic cardiomyopathy is determined. It is established that in patients of different age crucial importance plays not the age factor, but side cardiotoxic effect of antipsychotics leading finally to development of the cardiac pathology. Keywords: Antipsychotics; Cardiotoxicity; Neuroleptic cardiomyopathy; Electrocardiogram changes; Age effect As a result of active therapy of both the main mental and concomitant somatic pathology, the life expectancy of mental patients, in particular those suffering from schizophrenia, has increased significantly [1-5]. This process is accompanied by a significant increase in the duration of antipsychotic therapy (APT), thereby significantly lengthening the time of damaging cardiotoxic effects of antipsychotics (AP) on the heart, which is fraught with the development of severe life-threatening iatrogenic pathology-neuroleptic cardiomyopathy (NCMP) [6].
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