Electroactive material-based biosensors for detection and drug delivery.

Abstract

Electroactive materials are employed at the interface of biology and electronics due to their advantageous intrinsic properties as soft organic electronics. We examine the most recent literature of electroactive material-based biosensors and their emerging role as theranostic devices for the delivery of therapeutic agents. We consider electroactive materials through the lens of smart drug delivery systems as materials that enable the release of therapeutic cargo in response to specific physiological and external stimuli and discuss the way these mechanisms are integrated into medical devices with examples of the latest advances. Studies that harness features unique to conductive polymers are emphasized; lastly, we highlight new perspectives and future research direction for this emerging technology and the challenges that remain to overcome.