Abstract
Mature nucleated amphibian erythrocytes can be stimulated to undergo morphological changes resembling de-differentiation when exposed to small amounts of electric current. Puromycin and cyclohexamide will inhibit these morphological changes, and cytochemical staining indicates that RNA synthesis begins in concert with the changes in morphology. Autoradiographic studies show that the erythrocytes exposed to electric current synthesize RNA and protein whereas the erythrocytes not exposed to current do not make appreciable amounts of macromolecules. Electrophoretic separation of proteins from stimulated cells exhibit a band pattern different from that of unstimulated erythrocytes, and scintillation counting shows that some of the new proteins have been synthesized after electrical stimulation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
