Abstract
Plymen et al 1 Plymen C.M. Bolger A.P. Lurz P. Nordmeyer J. Lee T.Y. Kabir A. Coats L. Cullen S. Walker F. Deanfield J.E. Taylor A.M. Bonhoeffer P. Lambiase P.D. Electrical remodeling following percutaneous pulmonary valve implantation. Am J Cardiol. 2011; 107: 309-314 Abstract Full Text Full Text PDF PubMed Scopus (29) Google Scholar reported in the January 15, 2011, issue of The American Journal of Cardiology on electrical remodeling (changes on the electrocardiogram) after percutaneous pulmonary valve implantation (PPVI) in 99 patients with congenital heart disease and increased right ventricular end-diastolic volumes (RVEDVs) due to pulmonary stenosis, pulmonary regurgitation, and mixed lesions. The investigators found a mean approximate 7-mm decrease in QRS duration (QRSd) after PPVI in patients with predominantly pulmonary regurgitation; no change in QRSd in the total cohort; decreases in QRS, JT, and corrected QT dispersions; a fair correlation of RVEDV with QRSd before PPVI; and no such correlation after PPVI. Electrical Remodeling Following Percutaneous Pulmonary Valve ImplantationAmerican Journal of CardiologyVol. 107Issue 2PreviewSudden cardiac death in congenital heart disease is related to increased right ventricular end-diastolic volume (RVEDV), abnormalities of QRS duration, and QRS, JT, and QT dispersions. Surgical pulmonary valve replacement and percutaneous pulmonary valve implantation (PPVI) decrease RVEDV, but the effects of PPVI on surface electrocardiographic parameters are unknown. PPVI represents a pure model of RV mechanical and electrophysiologic changes after replacement. This prospective study sought to determine the effects of PPVI on surface electrocardiographic parameters: Ninety-nine PPVI procedures in patients with congenital heart disease (23.1 ± 10 years of age) were studied before, after, and 1 year after PPVI with serial electrocardiograms and echocardiogram/magnetic resonance images. Full-Text PDF Authors' ReplyAmerican Journal of CardiologyVol. 107Issue 12PreviewWe would like to thank Dr. Madias for his interest in and comments on our report. We take this opportunity to attempt to address some of the points raised. Full-Text PDF
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