Abstract
1. 1. Alanine and phenylalanine have been used to induce changes in short-circuit currents (AIC) across intestines taken from 5 different mammalian species. AIC was a hyperbolic function of amino acid concentration characterized by the parameters J m (maximum change in AIC) and K m (concentration needed to attain an AIC equal to half the J m ). 2. 2. K m but not J m was shown to remain independent of the species used (guinea-pig, pig, rabbit, rat and hamster). 3. 3. AIC determined K m constants showed good agreement with values obtained previously from direct measurement of alanine and methionine uptake into rabbit distal ileum. 4. 4. AIC measurements provide a rapid and specific means of characterizing a high affinity low capacity amino acid transport system common to different mammalian enterocytes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Comparative Biochemistry and Physiology -- Part A: Physiology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
