Abstract
Electrical Bioimpedance (EBI) is now a mature technology in medicine, with applications in clinical investigations, physiological research, and medical diagnosis (Schwan, 1999). The first monitoring application of bioimpedance techniques, impedance cardiography, date back to 1940. Since then, bioimpedance measurements have been used in several medical applications, from lung function monitoring and body composition, to skin cancer detection. A complete historical review is available in Malmivuo and Plonsey (1995). A medical imaging modality based on bioimpedance, Electrical Impedance Tomography (EIT) has also been developed (Bayford, 2006). EBI has been used to study the effect in the brain of spreading depression, seizure activity, asphyxia and cardiac arrest since 1950s and 1960s (Ochs & Van Harreveld, 1956), but the most important activities in electrical cerebral bioimpedance research has been during the last 20 years (Holder, 1987; Holder & Gardner-Medwin, 1988).
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