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Abstract
The time course of the impairment of both photic and spontaneous excitation of the retinal ganglion cells of cats is described for the 2 weeks following -y-irradiation (4200 rad) and is related to morphological signs of damage. Irradiation resulted in damage to the receptor cells. This did not affect the spontaneous activity of the ganglion cells during the following first eek, but later their firing patterns and firing rates were clearly changed. The first week was characterized morphologically by necrosis of the receptor cells. During the subsequent period vascular changes and degeneration of the neural retina became noticeable.
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