Elderly lung transplant recipients show acceptable long-term outcomes for lung transplantation: A propensity score-matched analysis.

Abstract

Although the performance lung transplantation (LTx) in the elderly (≥ 60years) has increased globally, the situation in Japan remains quite different, because the age limit at registration for cadaveric transplantation is 60years. We investigated the long-term outcomes of LTx in the elderly in Japan. This was a single-center retrospective study. We divided the patients into two groups according to age: the younger group (< 60years; Y group; n = 194) and the elderly group (≥ 60years; E group; n = 10). We performed three-to-one propensity score matching to compare the long-term survival between the E and Y groups. In the E group, the survival rate was significantly worse (p = 0.003), and single-LTx was more frequent (p = 0.036). There was a significant difference in the indications for LTx between the two groups (p < 0.001). The 5-year survival rate after single-LTx in the E group was significantly lower than that in the Y group (p = 0.006). After propensity score matching, the 5-year survival rates of the two groups were comparable (p = 0.55). However, the 5-year survival rate after single-LTx in the E group was significantly lower than that in the Y group (p = 0.007). Elderly patients showed acceptable long-term survival after LTx.