Abstract
Durable and biocompatible superhydrophobic surfaces are of significant potential use in biomedical applications. Here, a nonfluorinated, elastic, superhydrophobic film that can be used for medical wound dressings to enhance their hemostasis function is introduced. The film is formed by titanium dioxide nanoparticles, which are chemically crosslinked in a poly(dimethylsiloxane) (PDMS) matrix. The PDMS crosslinks result in large strain elasticity of the film, so that it conforms to deformations of the substrate. The photocatalytic activity of the titanium dioxide provides surfaces with both self-cleaning and antibacterial properties. Facile coating of conventional wound dressings is demonstrated with this composite film and then resulting improvement for hemostasis. High gas permeability and water repellency of the film will provide additional benefit for medical applications.
Highlights
Durable and biocompatible superhydrophobic surfaces are of significant infections.[4]
Superhydrophobic film that can be used for medical wound dressings to enhance their hemostasis function is introduced
The film is formed by titanium dioxide nanoparticles, which are chemically crosslinked in a poly(dimethylsiloxane) (PDMS) matrix
Summary
The small contact area reduces the adhesion area available to individual platelets hindering the hemostatic mechanisms.[8d] Figure 4f shows that blood repellency of the PDMS/TiO2 film modified wound dressing is still maintained when the film is stretched. Figure 4j shows that when the incision was bandaged by the PDMS/TiO2 modified wound dressing, no bleeding was observed even if the joint of finger was bent. By using a PDMS/TiO2 film, the wound dressing can effectively block leakage of blood while maintaining gas permeability even under water Given these special properties, surfaces covered with this film will potentially combat contamination caused by blood adhesion and help to avoid infections transferred by blood
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