Abstract
Parmentier and Fuhrer have suggested, empirically, a hyperbolic equation to describe the force F versus punch displacement x curve during the compression of a tablet. It is shown in the writing to follow that in the case of dicalcium phosphate dihydrate (Ditab) the equation fails and that a different type of function for the relation between F and x applies. This function has been derived, theoretically, from the Athy—Heckel equation. It has been tested, and fits experimental data well.The effect of various levels of magnesium stearate is demonstrated, and it is shown that external friction measurements reported by Fukumori and Carstensen are in line with the energy transfer behavior of dicalcium phosphate dihydrate on an instrumented press. The effect of magnesium stearate level on the parameters of the F-x relation has been determined.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
