Abstract
ABSTRACTMedicated skin care products are available in various forms; ranging from lotions and creams to bandages and membranes. In this study, antibacterial particulate laden fibrous membranes (FMs) were prepared via electrospraying of tetracycline hydrochloride‐loaded poly(ε‐caprolactone) particles alongside electrospinning of thermoplastic polyurethane (TPU) fibers, through which both mechanical and biological aspects of a complete membrane system can be achieved. Random (R) and ordered (P and V) patterns of TPU FMs were afforded using a rotating collector. Water contact angle and bacterial inhibition zone tests were performed to assess suitability of the system specifically for wound care. Stress–strain and in vitro drug release tests were performed to assess suitability of newly developed systems specifically for hybrid membranes (HMs). The highest tensile strength (32.1 ± 4.9 MPa) with elasticity (104.2 ± 6.0%) and the most sustained release rate indicate HMs (P) are potentially suitable materials for wound‐care applications. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47105.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
