Abstract

The treatment of malignant lymphoma has undergone major changes in recent years. ABVD with or without radiotherapy for untreated Hodgkin lymphoma (HL) and CHOP-based combination therapy with anti-CD20 antibody rituximab for B cell non-Hodgkin lymphoma (B-NHL) have long been the standard of care. Type II anti-CD20 antibody obinutuzumab combination chemotherapy has become a new treatment option for indolent-B-NHL, and an antibody-drug conjugate against CD30 brentuximab vedotin combination chemotherapy has become the new treatment of choice for advanced-stage HL and CD30-positive T-NHL.

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