Abstract

The meetings on ‘Cell Biology, Signaling and Alternative Splicing’ and ‘Gene Expression and RNA Processing’ took place between 26 and 30 November 2007, in Bariloche, Argentina, and were organized by A. Kornblihtt, A. Srebrow, J. Caceres, A. Lamond and T. Misteli. Support was provided by the International Centre for Genetic Engineering and Biotechnology (ICGEB) and by the European Network on Alternative Splicing (EURASNET). ![][1] “El Sur tambien existe” However down here,down close to the roots,is where memoryforgets no memories.And there are those who struggleand there are those who try hardand this is how together they managewhat seemed impossible.The whole world knowsthat the South,the South also exists. Mario Benedetti (translated by J. Martinez) The heart of science also beats in the southern hemisphere, and in the last days of November 2007, in the middle of the southern spring, the RNA community met in Bariloche, in the beautiful Argentine Patagonia. Transcription and RNA processing were the focus of the combined meetings ‘Gene Expression and RNA Processing’ and ‘Cell Biology, Signaling and Alternative Splicing’. The organizers chose a lovely site, as well as an eclectic group of speakers and participants. The result was a stimulating mixture of science, lively poster sessions with students and postdocs, and hours of informal discussion. Here, from the 52 talks presented, we strive to highlight selected emergent themes and apologize to those speakers whose topics we have been unable to include. The meeting started with a Keynote Lecture from T. Cech (Boulder, CO, USA), whose talk on telomerase foreshadowed many of the subsequent topics. Telomerase, the enzyme that extends chromosome ends and thereby maintains chromosome integrity over infinite cycles of DNA replication and cell division, uses an RNA primer provided by the telomerase RNA—Tlc1 in budding yeast and Ter1 in fission yeast (Zappulla & Cech, 2006). Similar to spliceosomal … [1]: /embed/graphic-1.gif

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