Ekstremite yerleşimli sinovial sarkomun klinik sonuçları

Abstract

Aim: The aim of this study is to emphasize the demographic data, follow-up results and the importance of approach to
 these tumors of synovial sarcoma, which is a rare tumor in the extremities.
 Material and Methods: In this study, twenty patients who were operated on for extremity synovial sarcoma between
 2008 and 2018 at Dr. Abdurrahman Yurtaslan Oncology Hospital were retrospectively analyzed. Demographic information,
 surgical treatments, follow-up periods, recurrence and metastases of the patients were recorded.
 Results: Twenty patients with a diagnosis of synovial sarcoma with a mean age of 32.7 (range, 13 to 66) years were included
 in this study. According to the localization, it was observed that the tumors were mostly located in the thigh (25%), cruris
 (25%) and ankle (25%). It was observed that the tumor size was 5 cm or more in 70% of the patients. While 55% (n=11) of
 the patients had metastases at the time of diagnosis (lung), recurrence developed in 25% of the patients during follow-up.
 Wide resection was performed as the primary surgical treatment in 85% of the patients, while 75% received RT, only 30%
 received CT. 25% of patients died during follow-up. The mean survival time of the patients was 109.4±8.9 months. While
 the 3-year survival rate was 90%, the 5-year survival rate decreased to 80%. There was no significant difference in survival
 times according to gender, age, side, grade, tumor size, metastasis, RT, KT and recurrence status.
 Conclusion: In conclusion, synovial sarcoma is a rare malignant soft tissue sarcoma with high grade and high metastasis capacity.
 For understanding the characteristics of synovial sarcoma, multicenter studies with a larger number of patients are needed