Abstract

For the 21st time in a row, the Netherlands Society of Cardiology (NVVC), the Interuniversity Cardiology Institute of the Netherlands (ICIN), and the sponsor, Sanofi-Aventis, have supported the competition for the best three PhD theses on a cardiovascular subject published last year. The prize carries the name of one of the great Dutchmen in the history of cardiology: Willem Einthoven (1860-1927), the pioneer of the human ECG and winner of the Nobel Prize in 1924.

Highlights

  • In an analysis of all patients referred for renal denervation (RDN), we showed that two-thirds were excluded from treatment: 25 %

  • Of these patients appeared to have “white-coat” resistant hypertension and 12 % had a secondary cause of hypertension

  • This was remarkable since all referred patients had an extensive history of hypertension

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Summary

Introduction

Despite increasing interest in the functional relevance of epicardial stenosis and its beneficial effect on patient outcomes in the setting of stable ischaemic heart disease, it is important to realise that ischaemic heart disease goes beyond the domain of the coronary circulation that can be assessed by angiography and fractional flow reserve. These data suggest that the coronary microcirculation, which remains elusive to the interventionalist in contemporary angiography and fractional flow reserve-guided practice, plays a dominant role in the diagnosis and risk stratification in stable ischaemic heart disease patients.

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