Abstract
AbstractThe influence of amitrole (3‐amino‐1.2,4‐triazole) on growth, alkaloid formation and on some aromatic as well as ergoline pathway specific enzymes were studied in Claviceps strain, SD 58. In a phosphate‐rich medium the addition of amitrole can partially reverse the alkaloid‐depressing effect of phosphate. Using a typical fermentation medium amitrole reduces the activities of ergoline specific enzymes but increases drastically tryptophan synthase activity and to a lesser extent transaminases of aromatic amino acids.
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