Abstract
The effect of antihypertensive treatment for 12 weeks with one of three medications (ß-Blocker, calcium channel blocker, or diuretic versus placebo) on blood flow velocities in extra- and intracranial arteries were investigated in 71 patients suffering from hypertension. Evaluation of blood flow velocities was performed for extracranial arteries with a duplex sonography system and for intracranial arteries with a pulsed transcranial Doppler. Under resting conditions all measured flow velocities as well as flow patterns and turbulences in the bulbus of the carotid bifurcation remained unchanged throughout the trial despite effective reduction of blood pressure in the verum groups. This may indicate that patients with hypertension have intact cerebral autoregulation.
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