Abstract
The activity of nine anticoccidial drugs was investigated against Eimeria infections of chicken embryos. With Eimeria tenella, three parameters were used to assess the antiparasitic effects (a) mortality (b) focal lesions on the chorioallantoic membrane (CAM) and (c) oocyst production. Anticoccidial drugs against E. mivati were evaluated by estimating oocyst production only. Only three of the anticoccidials tested were found to have high activity when measured by all of the above criteria. All of the drugs tested reduced infections caused by E. tenella and E. mivati. With f. tenella, inhibition of CAM focal lesions and oocyst production proved to be more sensitive parameters than mortality of infected embryos. The number of sporozoites in the inoculating dose was important, particularly in the oocyst production studies because excessively large numbers of sporozoites did not result in high yields of oocysts. The application of chicken embryo infections with Eimeria for the study of anticoccidial drugs is discussed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
