Abstract

We evaluated a 25-year-old woman with multiple sclerosis who presented with the acute onset of a profound unilateral high-frequency, sensorineural hearing loss that resolved clinically within 10 days. Click-elicited brain stem-evoked responses were abnormal at the time of presentation and demonstrated only limited recovery over a follow-up period of 11 months. Magnetic resonance imaging disclosed a lesion in the eighth nerve root-entry zone and the cochlear nucleus. Our findings in this case support the hypothesis of eighth nerve root-entry zone involvement in sudden hearing loss in multiple sclerosis and reinforce the notion that click-elicited brain stem-evoked responses are useful primarily to evaluate the high-frequency regions of the auditory system.

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