Abstract
There is a temporal correspondence between some of the early components of the auditory brainstem potentials in cat and the negative peak of the triphasic nerve action potential recorded from selected points along the VIII cranial nerve. The intracranial portion of the VIII nerve in cat has a conduction velocity of 10 meters/s. The initial peak of the ABR, P 1a, is coincident with the negative portion of the triphasic VIII nerve action potential within the cochlea as recorded from the round window. The next peak (P 1b) of the ABR occurs 400 μs later and is coincident with the negative portion of the triphasic VIII nerve action potential recorded from just within the lateral border of the cochlear nucleus. These results are similar to studies of the human ABR that show waves I and II are correlated with activity of the VIII nerve. It is likely that waves P 1a and P 1b in cat are homologous to waves I and II in human. In cat, these first two peaks of the ABR can be distinguished in vertex to neck recordings but not in vertex to ipsilateral mastoid derivations.
Highlights
The correspondence between the components of auditory brainstem potentials recorded from the scalp of animals and those recorded from man are uncertain
The results of this study show that, in the cat, the initial two vertex positive components (Pla and Plb) occur coincident in time with activity in the distal and central portions of the VIII cranial nerve respectively
The initial component (Pla) Occurs coincident with the activity of the VIII nerve within the cochlea, and the second component (P~b) occurs approximately 400/~s later at the time VIII nerve activity has just passed into the cochlear nucleus
Summary
The correspondence between the components of auditory brainstem potentials recorded from the scalp of animals and those recorded from man are uncertain. In man there are up to seven principal vertex positive components beginning at approximately 1.8 ms after a moderately intense stimulus which are labelled sequentially by Roman numerals (I-VII). In most animals the number of vertex positive components can be up to six beginning at about 1.0 ms and labelled by their polarity (P for positive) and their approximate latency in ms or their sequence of occurrence (e.g., P1,2,3, etc.). The component in m a n which is of largest amplitude is wave V (Jewett and Williston, 1971) whereas in experimental animals it is wave P4 (cat, Achorand Starr, 1980; monkey , Allenand Starr, 1978), P3 (guinea pig, Wadaand Starr, 1983) o r P2 (rat, Plantz et al, 1974).
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
