Abstract
The initiating mechanisms of migraine attacks are very complex but may involve the cyclic adenosine 3',5'-monophosphate (cAMP) signaling pathway. It is unknown whether intracellular cAMP accumulation induces migraine attacks.
Highlights
IntroductionThe initiating mechanisms of migraine attacks are very complex but may involve the cyclic adenosine 3’,5’-monophosphate (cAMP) signaling pathway
The initiating mechanisms of migraine attacks are very complex but may involve the cyclic adenosine 3’,5’-monophosphate signaling pathway. It is unknown whether intracellular cAMP accumulation induces migraine attacks
Aim To investigate whether administration of cilostazol, which causes cAMP accumulation, may induce migraine attacks
Summary
The initiating mechanisms of migraine attacks are very complex but may involve the cyclic adenosine 3’,5’-monophosphate (cAMP) signaling pathway. It is unknown whether intracellular cAMP accumulation induces migraine attacks. Aim To investigate whether administration of cilostazol, which causes cAMP accumulation, may induce migraine attacks. Published: 18 September 2014 doi:10.1186/1129-2377-15-S1-A5 Cite this article as: Song et al.: EHMTI-0033. The phosphodiesterase 3 inhibitor cilostazol induces migraine-like attacks via cAMP increase. The Journal of Headache and Pain 2014 15(Suppl 1):A5
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