EHMTI-0027. The neuropathic pain in vascular dementia

Abstract

Methods 56 patients were diagnosed in the last two years with advanced vascular dementia according to clinical manifestations, vascular risk factors and neuroimaging which revealed brain atrophy and multiple focal lesions in the subcortical white matter. 21 of them suffered from neuropathic pain but were unable to reliably communicate their pain. So, we used Pain Assessment in Advanced Dementia Scale (PAINAD) whose total score ranges from 0 to 10 points, including mild pain (1-3), moderate pain (4-6) and severe pain (7-10). The lesions were 34% compressive-disc prolapse in the spine, producing sciatica or cervico-brachial nevralgia, 15%. were infiltrative as paraneopastic polineuropathy and 51% due to damage to the nerve itself by an intrinsec process-diabetic, alcoholic neuropathy, postherpetic neuralgia. The pain responded well to antiseizures and antidepressant medication.