Abstract
Designing biomimetic scaffolds that can provide an appropriate microenvironment in bone defects to accelerate bone regeneration may become the breach of bone tissue engineering. Herein, we present simple egg white (EW)-/eggshell (ES)-based biomimetic hybrid hydrogels to investigate their potential for promoted bone regeneration. The photopolymerized biomimetic hybrid hydrogels possessed porous structures, which may support cell growth. Remarkably, the addition of eggshells could benefit mechanical performance with good cytocompatibility. Moreover, biomimetic hybrid hydrogels could have effects on macrophages and regulate the osteogenic differentiation of human dental pulp stem cells, indicating their potential for enhanced bone regeneration. All of the results suggested that biomimetic hybrid scaffolds possess a promising prospect in bone tissue engineering with good bioactivity and low cost.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.