Egg consumption and risk of cardiovascular diseases, evidence from China Health and Nutrition Survey 2000–2011

Abstract

ObjectiveThe morbidity and hospitalization of CVDs in China have kept increasing since 2000, outpacing the GDP growth. CVD may bring heavier burden in the coming decade to Chinese people, economically and physically. There are evidence indicating the strong relationship between high plasma concentration of cholesterol and CVDs, but the association between CVDs and dietary cholesterol intake remains unclear. We therefore conducted a longitudinal analysis with multifactor adjusting models to assess the nonfatal myocardial infarction (MI) and stroke risks of egg consumption in a sample of Chinese adults.MethodFive rounds of China Health and Nutrition Survey from 2000 to 2011 were used in this study. 5289 non‐myocardial infarction or non‐stroke subjects >30y in 2000 and followed at least once in the subsequence rounds were included in the final analysis. Three consecutive 24h dietary recall was used to collect egg consumption data, and self‐reported nonfatal MI and stroke history at each follow‐up was used for the CVD diagnosis. Cox proportional hazards regression models with time‐dependent explanatory variables was conducted to compute relative risks and 95% CIs.ResultThe follow‐up time of the myocardial infarction(MI) patients was averagely 9.62 years, while that of the stroke patients was 9.59 years. In 2000, the average daily egg consumption of the whole population was 50.01±38.39g/day, while the figure slightly decreased in the year of 2011, at 46.52 ±34.18g/day. Adjusted for age, gender, education level, household income, urbanized level, geographic location, and individual behavioral factors (including drinking, smoking, physical activity level, weight status, and chronic disease history ), multivariate Cox regression analysis revealed that egg consumption was not a significant risk factor of the CVDs in this study(MI and stroke).ConclusionOur study shows no significant relation between egg consumption and CVD risks in this population of which egg consumption was mostly below 100g/day.Support or Funding InformationThe authors thank the team at National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, and the Carolina Population Center, University of North Carolina at Chapel Hill. The China Health and Nutrition Survey data collection was in part funded by research grants from the NIH (R01‐HD30880, DK056350, R24 HD050924, and R01‐HD38700) and the NIH Fogarty International Center and by the Chinese Center for Disease Control and Prevention. The content of the paper is solely the responsibility of the authors and does not necessarily represent the official views of the funders.This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.