Eficacia y seguridad de la lipotransferencia en el tratamiento del fotoenvejecimiento cutáneo

Abstract

IntroductionAging is an inevitable process that depends on genetic and environmental factors. Facial photoaging is an expression of the effect of ultraviolet radiation and can be prevented in many ways, among which fat transfer has become popular. ObjectiveTo evaluate the efficacy and safety of fat transfer in the treatment of skin photoaging. Patients and methodAn observational, analytical and longitudinal study was carried out in 43 patients with cutaneous photoaging at the Hospital Clínico Quirúrgico «Hermanos Ameijeiras», in the period between February 1st, 2019 and February 28th, 2020. Lipoblotting was performed by the Coleman method. The nano-fat type adipose tissue was processed and administered. The response to treatment was used from the clinical point of view (3 months after having performed the procedure) using the Glogau Photo Damage Classification Scale, the Global Esthetic Improvement Scale and the Evaluative Scale of the severity range of the nasolabial fold (WSRS), with photographic evidence and with a surface microscope. ResultsAfter treatment, there were significant changes in the Glogau photodamage classification scale (P = 0.0002), in the Global Esthetic Improvement Scale (P = 0.019) and in the Evaluative Scale of the range of severity of the nasolabial fold (P = 0.0231). The adverse events found were pain, inflammation and ecchymosis; of mild or moderate intensity, without permanent consequences in individuals. The degree of satisfaction reported by the patients was good (4.7%) and very good (95.3%) (P = 0.0011). ConclusionsStem cell assisted fat transfer is effective and safe in correcting the signs of facial photoaging, with a high degree of patient satisfaction.