Abstract
Getting on with it: A common problem with hydrophobic non-natural base pairs—the inefficient extension following such a base pair—is reduced by using the methylpyridone scaffold, which simultaneously limits another frequent problem of non-natural bases: mispairs with deoxyadenosine. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z601272_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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