Abstract
AbstractAn Ir(III) catalyst was used for the first time to realize the synthesis of quinazolines by C−H bond activation/cyclization with N‐alkoxyamides as amidation reagents. This reaction has the advantages of wide substrate adaptability, good to excellent yields under mild conditions, short reaction times, and no need for an inert atmosphere. Importantly, several quinazolines from bioactive compounds were obtained, which highlights the importance of this new method.
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