Abstract

When 4-fluorophenol was refluxed with excess of t-butyl chloride in the presence of various catalysts, e.g. Envirocat EPZG, EPZ10, EPIC, sulfated zirconia, natural kaolinitic clay, zirconium nitrate, zinc chloride and bismuth nitrate, the product obtained was 2,5,di- t-butyl 4-fluorophenol in excellent yield.

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