Abstract

An efficient route to two 3- O-acyl-2-deoxy-4,6- O-isopropylidene-2-trichloroacetamido- d-glucopyranosyl trichloroacetimidate donors is reported. As demonstrated for the 3- O-acetyl derivative, these building blocks are exquisite β- d-glucosamine donors when reacted either with simple alcohols or with complex oligosaccharides. Besides, their protection pattern is compatible with selective deprotection and subsequent chain elongation at O-3 of the newly incorporated glucosamine residue.

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