Abstract

A proficient and meticulously designed diasterioselective, multicomponent, one-pot synthesis of densely substituted piperidine derivatives has been elaborated using polystyrene sulfonic acid catalyst via tandem reactions of 1,3-dicarbonyl compounds, aromatic aldehydes and various amines. Shorter reaction times, high yields and a polymer-supported inexpensive catalyst are the noteworthy aspects of the scaffold.

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