Abstract
A parallel and advantageous multi-component one pot reaction has been developed utilizing domino Aldol condensation–Michael addition–Suzuki coupling approach for a variety of 2,3-disubstituted highly functionalized quinolines. The domino reactions of 2-chloro-3-formylquinolines, 1 acetophenones, 2 and distinctive boronic acids, 3 were carried out utilizing PdCl2(PPh3)2/tripotassium phosphate/ethanol–water system. At 80°C they gave diversified functionalized quinolines in good yields.
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