Efficient gene editing in tomato in the first generation using the clustered regularly interspaced short palindromic repeats/CRISPR-associated9 system.

Abstract

During the past 12 years, there has been rapid development of genome-editing strategies that make it possible to directly target regions of genes in a DNA sequence-specific manner. Two of these strategies, zinc finger nucleases ([Urnov et al., 2010][1]) and transcription activator-like nucleases ([