Abstract
We wereinterested in nuclease activity of the Cu complexes havingDNA binding groups since it would provide valuable infor-mation in developing sequence specific artificial nucleases.Several acridine conjugates of mononuclear Cu, Zn com-plexes had been reported, where strong binding through anintercalation of acridine moiety to DNA was the main factorfor the nuclease activity, yet the cleavage mechanisms werenot well established.
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