Efficient Cleavages of Ribonucleoside 2′,3′-Cyclic Phosphates and Ribonucleotide Dimers Catalyzed by β-Cyclodextrin Attached with Diethylenetriamine-Zinc(II) Complex

Abstract

Abstract The complex between a modified β-cyclodextrin, which is attached with a diethylenetriamine residue at the primary hydroxyl side, and zinc(II) ion effectively and homogeneously catalyzes the cleavages of the 2′,3′-cyclic monophosphates of ribonucleosides and the ribonucleotide dimers. The magnitude of the catalysis is highly dependent on the kind of the nucleic base in the substrates.