Abstract
Abstract Heptakis(6-O-pivaloyl)-β-cyclodextrin, prepared in high yield by pivaloylation of β-cyclodextrin (β-CD), was treated with α,α-dimethoxytoluene in the presence of (+)-10-camphorsulfonic acid to give a 46% yield of eight-membered interglycosidic benzylidene acetal, 31,22-O-benzylidene-61,62,63,64,65,66,67-hepta-O-pivaloylcyclomaltoheptaose. Further reductive ring-opening reaction or acid hydrolysis of the benzylidene group gave versatile intermediates for regioselective modification of β-CD.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.