Abstract
The acetalisation of aliphatic and aromatic aldehydes is achieved in a basic medium by using catalytic amount of Ti(IV) chloride in MeOH in the presence of NH 3 or Et 3N. The present protocol shows many advantages over the well known base or acid catalysis: in fact, in contrast to base-promoted acetalisation, aldehydes with electron-rich carbonyl groups react easily, enolizable aldehydes do not undergo aldol condensation and, in contrast to acid-catalysis, migration of the double bond does not occur in the preparation of α, β-unsaturated acetals. [Display omitted]
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