Abstract
The synthesis of multi-substituted 1-aminoisoquinolines from aminopyridine pivalamides with alkynes by Rh(III)-catalyzed CH activation coupling has been investigated. This method proved to be tolerant of synthetically versatile functional groups, and provided access to a few highly substituted isoquinoline derivatives with remarkable fluorescence properties in moderate yields.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have