Efficiency of specific prevention of pneumococcal infection at patients from risk groups in Krasnoyarsk region

Abstract

Aim was to study efficiency of specific prevention of pneumococcal infection at patients from the risk groups in Krasnoyarsk region. 12 080 patients with chronic lung diseases, chronic heart failure and diabetes mellitus were examined. The special questionnaire which included anamnesis assessment within the year previous bacterinations and anamnesis of basic disease within a year after bacterination was developed for assessment of clinical performance of bacterination. Immunization against pneumococcal infection was carried out to the following categories of patients: 41.08% with chronic heart failure, 28.44% suffering from diabetes mellitus, 30.07% with chronic lung diseases, 2.4% had pneumonia. 9986 (82.67%) were vaccinated with 13th inoculated by the valent pneumococcal conjugated vaccine, among them the combined bacterination with flu – 5070 (41.97%). By a pneumococcal polysaccharide vaccine were vaccinated – 1967(16.28%), from them it was single-step with flu – 1181(9.83%). Thanks to carrying out in the region of large-scale campaign for prevention of pneumococcal infection positive takes were received: the number of exacerbations or decompensations of basic diseases was reduced by 3 times, the number of hospitalization decreased by 11.5, the case rate pneumonia decreased by 4.8, and a acute respiratory virus infection or flu by 6.6. The received results testify to high efficiency of bacterination against a pneumococcal infection according to the prevention of development of pneumonia, depression of the case rate respiratory infections, reduction the number of hospitalization concerning exacerbations or decompensations as a result of stabilization of current disease.