Efficiency of local application of tranexamic acid during augmentative mammoplasty

Abstract

Surgical patients are often at risk of bleeding, which in some cases may even require blood components transfusion. In addition, bleeding provokes the hematoma development, which remains a rather common complication in surgery. Despite the fact that specialists apply post­operative blood pressure monitoring, compression therapy and drainage to prevent the development of such complications, hematomas are marked in plastic surgery at 1 — 15 %.The aim — to increase the augmentation mammoplasty surgery effectiveness by reducing perioperative and postoperative blood loss with tranexamic acid topical use.Materials and methods. 29 women to whom the augmentation mammoplasty was performed for the breast shape restoration, were supervised in the period from 2015 to 2018. Patients were divided into 2 groups. In the first group (n = 10) 10 ml of tranexamic acid were additionally introduced into the implant pocket for haemostasis, in the second group (n = 19) tranexamic acid was not used.Results and discussion. All patients completed the in­patient treatment according to the plan and were discharged on the second and third day after surgery. At control of the drainage fluid, the haemorrhagic and serous­haemorrhagic exudate was obtained from 25 to 90 ml per day after the intervention. The volume of the exudate decreased in the first group more rapidly.Conclusions. The tranexamic acid local application allows to reduce the amount of blood loss in the postoperative period, the duration of the drainage systems functioning and, accordingly, reduce the complications risk associated with the presence of drainage and contrapertures.