Abstract
The purpose of this work was to study physical-chemical, antimicrobial and toxicological -hygienic properties of the developed antiseptic for external application «Vitasept-SKZ». It has been established that developed spirit solution «Vitasept-SKZ» for external application possesses physical and chemical properties satisfactory to sanitary regulations for antiseptics. In working concentration the drug action results in absence of growth of all museum test cultures of microorganisms within 1 and 2 minutes. In the quantitative suspension test the reduction factor of all test cultures of microorganisms within 1 minutes «Vitasept-SKZ» exceeded 6 lg. For hygienic hand antiseptics the given handwash causes the reduction factor of E.coli test-culture more than 4 lg. In test of microbiological cleanliness microorganisms Enterobacteriaceae bacteria, Р aeruginosa and S. аureus were determined. The developed antiseptic solution pertains to practically nontoxical and low-dangerous substances with low irritant, cumulative properties, does not demonstrate irritating and sensitizing action, being hygienic safe. Stability tests revealed no considerable changes in appearance and physical and chemical properties of the drug. Developed spirit solution «Vitasept-SKZ» for external application can be recommended for use in public medical health care units.
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