Abstract

This work examines the issues of obtaining compositions with adaptogenic and prebiotic effects, quality control, as well as assessment of their biological effects. Inulin was analyzed by reverse-phase HPLC with refractometric detection. In vivo studies were performed using 50 male Wistar rats, 6 weeks old, with an initial body weight of 158 ± 3 g. To study the intestinal microbiota, DNA was extracted using the DNA-Sorb-S kit. As a result, compositions have been developed that include functional food ingredients based on spinach leaves and quinoa grains, containing at least 96.0% inulin. The established beneficial effect of adaptogenic compositions with inulin on the intestinal microbiota opens up the potential for their use to maintain the optimal composition of the intestinal microbiota.

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