Abstract
An open label, optional titration trial to evaluate the efficacy, tolerability and safety of Valsartan 80mg o.d/Valsartan 160mg o.d. in patients with mild to moderate hypertension treated for eight weeks. Twenty consenting subjects (11 males and 9 females) aged 29 to 79 years (mean age 48. 2 ± 11. 9yrs) were treated for eight weeks with Valsartan. Ten of the 20 subjects (50%) had diastolic blood pressure (DBP) end point below 90mmhg while 4 had a DBP end point of 90mmHg. There was significant drop in DBP of the entire study population from 101.8± 6. 1mmHg to 89.9 ± 10.0 mmHg (P Keywords : hypertension; Valsartan; tolerability; efficacy Nigerian Medical Practitioner Vol. 50 (2) 2006: pp 27-32
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