Efficacy research of enhanced recovery after surgery in the perioperative patients with colorectal cancer resection

Abstract

Objective To explore clinical application effects of enhanced recovery after surgery in colorectal cancer patients. Methods Retrospective clinical data analysis of 1 390 patients with colorectal cancer between January 2011 and December 2015, they were divided into ERAS group and traditional group according to whether colorectal cancer patients implemented ERAS important five factors in the perioperative period. Recovery efficiency and the difference between health care costs were compared and analyzed between ERAS group and Traditional group according to quality of rehabilitation. Results There was no statistical difference between two groups about postoperative rehabilitation quality such as mortality, unplanned readmission (Χ2=2.102, P=0.147; Χ2=0.279, P=0.662) and unplanned reoperation (Χ2=0.013, P=0.908; Χ2=0.606, P=0.527) 30 days after operation, ERAS postoperative complications incidence is lower than the traditional group in colorectal cancer (Χ2=4.772, P=0.031); There was a statistical difference between two groups on average (Χ2=2.19, P=0.031; Χ2=2.03, P=0.045) and postoperative (Χ2=2.15, P=0.034; Χ2=2.11, P=0.036)hospitalization day. There was a statistical difference between two groups on total cost (t=-4.61, Z=-7.85), medicine fee (Z=-3.87, Z=-5.50), services cost (Z=-3.87, Z=-5.50), examinations cost (Z=-3.54, Z=-6.46), and materials cost (Z=-3.33, Z=-5.57), bed fee (Z=-4.28, Z=-14.84) (P<0.01). There was a statistical difference between two groups on average daily hospitalization cost (t=2.01, P=0.046; Z=-8.14, P<0.01). Conclusion Application of enhanced recovery after surgery in patients with colorectal cancer is safe and effective by reducing complications, shortening hospitalization time and reducing service charge, examinations, and materials, medical and other expenses, thereby the significant advantages and economic benefits have been showed. ERAS improves the clinical medical quality, reduces the hospitalization expenses, and it is helpful to promote tertiary public hospital comprehensive service ability. Key words: Colorectal neoplasms; Fast track surgery; Perioperative; Clinical application effects