Abstract
During the past decade there has been a considerable difference of opinion as to the comparative efficiency of ephedrine and its synthetic derivatives in the treatment of nasal obstruction. Previous attempts to determine their specific action in the obstructed nose have not provided reliable data, largely because of the limitations of the methods employed. In 1936 Schur and I 1 first described a new method for the quantitative measurement of nasal patency. The patency of the nasal airway was easily and accurately determined in terms of resistance to nasal air flow. 2 This method was employed to evaluate the rate and degree of nasal shrinkage. The present study deals with the quantitative effects of ephedrine, cocaine and some proprietary synthetic preparations administered in different concentrations and forms on the erectile tissue in the pathologic nose. APPARATUS AND PROCEDURE The apparatus (fig. 1) consists of a nasal catheter ( F ), a flowmeter
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