Abstract

One of the CDC 2011 1A recommendations for the prevention of Catheter-Related Bloodstream Infections (CRBSIs) is the use of antimicrobial Central Venous Catheters (CVCs). Mostly, CRBSIs are mono-microbial in nature and are well studied; however, poly-microbial infections, which are more difficult to treat, are less understood. Therefore, this study was designed to evaluate the effectiveness of Chlorhexidine-Silver Sulfadiazine (CH-SSD), Minocycline-Rifampin (MR), and Silver-Carbon-Platinum (SCP) treated CVCs in reducing mono- and poly-microbial colonization's under in vitro conditions.

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