Abstract
Chronic respiratory disease (CRD) is one of the most important veterinary diseases in Bangladesh and all over the world. Mortality, reducing of weight gain and increasing of feed conversion ratio (FCR) are caused by CRD. Several drugs are used for prevention and control of Mycoplasmosis. It is caused by Mycoplasma gallisepticum (MG). Tylosin and Tiamulin are effective on M. gallisepticum. By considering generating resistance against antibiotics that is effective on MG, studying the effect of these drugs in the treatment and prevention of Mycoplasmosis in birds were the purpose of this research. In this study, 36 layer birds (MG positive) of 25 weeks aged divided in three similar groups (A, B and C) contain 12 birds in each group. In group A; Tylosin was administered after mixing with 2.5 gm in 1 L drinking water, for Group B; Tiamulin was administered after mixing with feed @ 0.45gm/kg feed and Group C; Control (No antibiotic was given, only common feeding). The Serum Plate Agglutination (SPA) test was conducted; in positive cases granules were formed slowly which could be seen during rocking. In the negative case, no such granules were formed. Overall 6 and 9 serums shown negative SPA test in Group A and Group B, respectively. Therefore, the efficacy of Tylosin was 50.00% and the Tiamulin was 75.00% which resemble statistically significant (P<0.05). In control group, 5 birds were died during experiment. It can be concluded that usage of these antibiotics especially Tiamulin can be essential in the treatment and prevention of Mycoplasmosis in birds.Res. Agric. Livest. Fish.4(3): 187-191, December 2017
Highlights
In Bangladesh poultry farms are growing fast for the last two decades
Group A contained 12 birds were treated with Tylosin, Group B contained 12 which were treated by Tiamulin and Group C contained rest of 12 birds considered for control (No treatment was given)
AFive birds were died during experiments * Statistical significant variation between the efficacy of Tylosin and Tiamulin was present (P value
Summary
In Bangladesh poultry farms are growing fast for the last two decades. About 89% of the rural households rear poultry at either subsistence or commercial level (Anonymous, 1998). Infectious bursal disease accounted for 33% of total deaths in the commercial broiler industry, while salmonellosis, mycoplasmosis and Newcastle disease caused 16.9%, 26.2% and 9.8% loss, respectively, in breeding flocks. MG infection causes significant economic losses to the poultry industry throughout the world. Especially antibiotics have been used to treat flocks infected with MG and MS in order to reduce severity of clinical signs, lesions and production losses (Bencina and Bradbury, 1992). Such treatment can reduce severity of disease, economic losses, populations of Mycoplasmas, but does not eliminate MG and MS from the infected poultry flock. The present study was conducted to know the efficacy of tylosin and tiamulin against mycoplasmosis in layer birds
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